@jfabiani : I think you have not missed much.
Often, people are telling me, Python is sooo complicated when it comes to installing extensions. When I ask, I usually find that they are not using Python but Anaconda or some other setup…
The only bad thing I can say about pip is that pip.exe is useless and should get dumped and people should just use python -mpip instead.
@Sparky : Where does Conda get the info that a package is not compatible? For me that looks more like a Conda problem than for wxPython.